Statins and Cholesterol

Statins are among the most extremely suggested and commercially effective drugs in modern-day society, because of their ability to reduce LDL-cholesterol as well as lower the risk of establishing cardio illness. Find out more about the background, system, as well as negative effects of statins in this episode of Medicurio.

Various other lipoprotein particles:
You might have come across LDL cholesterol as “poor” cholesterol due to the fact that it blocks the capillary with plaque. Its counterpart, HDL or “great” cholesterol does the contrary – HDL fragments move throughout the bloodstream as well as choose up any kind of cholesterol it discovers as well as brings it back to the liver. Oftentimes, plaque development is reliant on both exactly how much LDL as well as how little HDL there remains in the blood.

Dr. Endo’s story on his exploration of compactin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108295/

CVD Risk Calculator by the American College of Cardiology: http://tools.acc.org/ASCVD-Risk-Estimator-Plus/

Recommendations:

Hajar R. Statins: Past and Present. Heart Views: The Official Journal of the Gulf Heart Association. 2011; 12( 3 ):121 -127.

Thompson, P. D., Clarkson, P., Karas, R. H. (2003 ). Statin-associated myopathy. Journal of American Medical Association, 289( 13 ): 1681-1690.

Golomb, B. A., & Evans, M. A. (2008 ). Statin Adverse Effects: A Review of the Literature as well as Evidence for a Mitochondrial Mechanism. American Journal of Cardiovascular Drugs: Drugs, Devices, as well as Other Interventions, 8( 6 ), 373– 418.